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India’s COVID Surge: The Curious Facets of U.S. Response

The volume and tenor of pleas for help escalated to new heights this past week as India was engulfed in the pandemic.

You’ve likely seen images of numerous funeral pyres and many graves along with sick outside overfull hospitals.

Apart from the pyres, it looks like Wuhan in January 2020, the U.S. in March 2020, and Brazil at the end of this March.

And yet there is something really wrong here, very off. The case counts and deaths are truths which can’t be escaped but the insistence the U.S. somehow is failing to meet India’s needs is off base.

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All that’s left of a couple thousand word post I wrote and wrote, and  then rewrote over the last several days is what remains above.

The situation over this past weekend changed rapidly, thought the angry ranting at the U.S. and Big Pharma never let up.

The Biden administration issued a couple of statements between Sunday and Monday about the steps it would take to aid India, which included COVID testing kits, PPE, oxygen, therapeutics for treatment, raw materials for vaccine production, and funding to ramp up capacity of India’s own vaccine producer, BioE.

The media did its usual weak sauce reporting.

Not a single outlet noted extremely curious facets about the Biden administration’s outreach to India:

• U.S. National Security Adviser Jake Sullivan spoke with his counterpart, India’s National Security Advisor Ajit Doval this weekend;

• There are no reports of Prime Minister Mahendra Modi contacting Biden to ask for help though they have spoken in the last 24 hours (perhaps as recently as this morning Eastern Time);

• There was scant coverage of U.S. Secretary of State Antony Blinken talks at least a week ago with his counterpart, India’s External Affairs Minister Subrahmanyam Jaishankar, regarding COVID and vaccines.

Why did the National Security Adviser play such a big role, with the White House statement issued by NSC office?

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In the mean time invective against the Biden administration and Big Pharma has continued, some of it based in what looks like weak and less-than-thorough reporting.

Claims that Big Pharma has decided profits come before the lives of India’s people follow reports that Big Pharma refused to give India patents or transfer intellectual property.

Except that Big Pharma is represented in India by AstraZeneca, which is making their adenovirus-vector vaccine in country. It’s the same vaccine which has been used in Europe, and is still in FDA safety review here.

India also has its own Big Pharma in Bharat Biotech, which has developed Covaxin vaccine in collaboration with Washington University School of Medicine in St. Louis, Missouri. The vaccine left Phase 3 trials in early January.

Yet intelligent people continue to harangue the U.S. and Big Pharma about their refusal to help India with the IP needed for licensing. They retweet stuff like this:

The account that wrote this was opened only weeks ago in January 2021. There’s almost nothing in its profile to suggest this is a human with credible background education or experience; the account hasn’t been validated by Twitter. Note the number of times this has been shared by retweet or quote tweet, yet the majority of roughly 6000 tweets by this account are about pop culture.

This is the kind of social media content which ramped up tension around U.S. response to India’s ongoing COVID surge and continues to do so because it remains uncontested.

The issue the tweet focused on was vaccine manufacturers’ request for indemnification by countries which use its vaccine or licensing to manufacture vaccines. How odd that an account tweeting about beauty products and the Kardashians chose to phrase indemnification this way.

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One of the reasons the U.S. National Security Adviser may be involved is the lack of an effective top-level response by India’s government to the surge. From Reuters via Yahoo:

NEW DELHI (Reuters) -India’s government has decided to leave the import of COVID-19 vaccines to state authorities and companies, two government officials told Reuters, a decision that may slow acquisitions of shots as a second wave of the pandemic rips through the country.

They said Prime Minister Narendra Modi’s government would instead aim to support domestic vaccine makers by guaranteeing purchases from them. The government this month paid Indian producers in advance, for the first time, for vaccine doses.

Under fire for his uneven handling of the world’s worst COVID-19 surge, Modi has opened vaccinations for all adults from next month but supplies are already running short.

Negotiations between countries on exports/imports are usually handled by their state departments or external affairs and not at lower state/province level. What amounts to the transfer of technology between a nation and individual states is a security risk, let alone problematic for individual pharmaceutical companies.

This is likely why the initial agreement between the U.S. and India’s national security advisers addressed shipment of supplies and other support but not vaccines, technology, or licensing.

It surely didn’t encourage the Biden administration to see how badly Modi has bungled handling the pandemic:

In late January, Modi indulged in a smarter version of Trump’s March 10, 2020 remark, “We’re prepared, and we’re doing a great job with it. And it will go away. Just stay calm. It will go away.”

Addressing the World Economic Forum’s online Davos Agenda Summit, PM Modi said India has beaten all odds to battle the pandemic. “When Covid-19 arrived, India had its share of problems. At the beginning of last year, several experts and organizations had made several predictions that India would be most affected by the pandemic. Someone had even said that 700-800 million would be infected and someone had said that over two million Indians would die from the pandemic. Looking at the condition of countries with better health infrastructure, the world was right in worrying about us,” he said.

“India, however, took a proactive public participation approach and developed a Covid-specific health infrastructure and trained its resources to fight Covid,” the PM added.

This was a mere 12 weeks ago; it was complete hogwash and hardly the stuff needed to instill confidence. India’s situation deteriorated greatly after Davos because Modi failed to take any effective measures to mitigate COVID’s spread in advance of a weeks-long major religious holiday, the Hindu observation of Kumbh Mela.

Nor has it helped develop trust in Modi and his government when they have demanded Twitter hide tweets critical of Modi’s COVID response from Indian public view.

Faith in the individual Indian states is tenuous at best; there are far too many anecdotes about state governments lying about COVID response and health care resources.

This is an insane level of denial:

Amid reports of patients and hospitals struggling to find and maintain oxygen supply, Uttar Pradesh Chief Minister Yogi Adityanath has asked officials to take action under the National Security Act and seize the property of individuals who spread “rumours” and propaganda on social media and try to “spoil the atmosphere”.

Mr. Adityanath asserted that there was no shortage of oxygen supply in any COVID-19 hospital – private or government-run – but that the actual problem was blackmarketing and hoarding.

The state of Uttar Pradesh is expending more resources on suppressing “rumours” than on demonstrating to the public there is ample oxygen and other resources for COVID therapy.

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This level of narcissism, gross incompetence, and denial in another country’s leadership isn’t something the U.S. can fix. Obviously the U.S. is still struggling with cleaning up after its own run-in with a white nationalist populist who was narcissistic and grossly incompetent as well as corrupt.

We’re still playing catch up because the Trump administration obstructed a peaceful and efficient transition, what with Trumpist GSA Administrator Emily Murphy refusing to turn over the keys to Biden’s team after the election. We’re not as far along as we should be with vaccinating the public because there was no federal COVID program when Biden was inaugurated and insufficient amounts of vaccine had been ordered by Trump.

Not to mention the January 6 attempt to overthrow the government and the Big Lie which continues to interfere with outstanding transition issues.

But the U.S. somehow bears some responsibility for the mounting disaster in India?

Otherwise smart people are trashing both the U.S. and their own cred with demands to remedy Modi’s manifold failures; others insist immediate action in spite of global inaction for decades on pandemic preparedness.

Where was all this concern when Trump killed the pandemic monitoring program instituted under Obama?

Where is the awareness of the security risks posed by a failing state like India, which already has patents?

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There’s one more element in this mix which may explain the presence of the National Security Adviser in the aid offering to India.

Granted, I’m not certain how to get a handle on the risk involved, but some of the intellectual property and technology isn’t as benign as a Play-Doh Fuzzy Pumper or an Easy-Bake Oven. It can be militarized and its output weaponized.

When talking about some of the COVID vaccines, we’re talking about development which began as military programs. Research for adenovirus-vector vaccines now used against COVID began in the 1950s inside the Defense Department; a vaccine was developed and distributed to military personnel for more than two decades to prevent acute respiratory disease associated with adenovirus infections. This vaccine didn’t become part of the scheduled vaccines American civilians receive, just as they didn’t receive anthrax vaccines.

How much of the limitations we have seen tossed around in social media, attributed to Big Pharma greed, are really carefully parsed concerns about the potential for the vaccine IP and technology to be acquired by hostile entities for weaponization?

Can we really blame any legitimate pharmaceutical company for expecting indemnification against the misuse of their product, IP, or technology considering this kind of exposure? Let alone the potential claims against them for extremely rare side effects which may be worsened by incompetence in treatment, ex. treating unusual clotting events with blood thinners which may exacerbate the clotting.

But this goes to the lack of global systemic preparedness for pandemic. It’s a global problem, not one for which the U.S. bears sole responsibility.

Imagine the possible blowback from questionable social media accounts with negligible provenance should the U.S. under the Biden administration choose to arbitrarily “Free the patents!” as so many demanded this past week over social media, without due diligence about the security risks these new vaccine technologies pose.

This pandemic requires us to imagine this and a lot more. We need to think systemically, more deeply and widely.

This includes thinking ahead to where will the next crisis begin, because it’s only a matter of time.

185,963

Here’s the topic Donald Trump and the Republican Party are doing everything they can to avoid:

It’s also the single biggest reason not to vote for Donald Trump.

I think Drew Gibson put it best in a tweet today:

The White House can put all the spin on their “Zapuder tape” they want. It won’t change the fact we can see they are killing us through police brutality and COVID-19.

It won’t change the fact Joe Biden was welcomed in Kenosha by community leaders, spoke with shooting victim Jacob Blake and met with Blake’s family — none of which insensitive racist Trump could bring himself to do.

It won’t change the fact Trump failed to boost U.S. manufacturing as he promised in 2016. Instead he set off an unnecessary trade war implementing tariffs which not only inflated consumer prices in the U.S., damaged demand for U.S. commodities, but encouraged the burning of Amazon rain forest for farmland in Brazil, which sold more soybeans to China.

It won’t change the fact that the Trump administration still has no effective response to COVID-19, allowing states to continue to fight on their own as more a thousand Americans die each day from the disease. At this rate 300,000 Americans will die of COVID-19 this year.

It won’t change the fact that no one in their right mind sees the Trump administration’s politicized hyper-speed development of a COVID-19 vaccine as anything more than a ploy for re-election purposes.

It won’t change the fact that +30% of college football players who’ve tested positive for COVID-19 developed myocarditis which may inhibit their ability to play in college and professionally — and none of this had to happen had Trump done his job.

It won’t change the fact the Trump administration and the GOP senate are allowing children to go hungry, ignoring mounting food insecurity and growing numbers of  unemployed with 1.6 million new claims filed this week.

It won’t change the fact that evictions and foreclosures are creating another crisis surpassing that of 2007-2009.

But keep spinning, Kelly McEnany. Maybe you’ll survive the failed Trump years and earn yourself a gig spinning numbers for a TV game show as your next gig.

This is an open thread.
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UPDATE-1 — 6:15 P.M. ET —

Wonder what the White House will do next to hide this?

This is bad. I wonder if they’ll care, though, since they’ve fucked up the U.S. Postal Service so badly overseas military votes may not get counted in a timely fashion.

We should be pounding on Esper to help active duty military to vote.

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UPDATE-2 — 8:00 A.M. ET FRIDAY —

Oh, not good. Media have been arguing about sourcing behind Jeffrey Goldberg’s piece in The Atlantic. AP verified some, and Washington Post followed up as well. But WaPo’s team published a piece which is just as blistering as Goldberg’s.

See Trump said U.S. soldiers injured and killed in war were ‘losers,’ magazine reports

We still aren’t told who the sources are but my money is on Jim Mattis being one of them. Goldberg wrote a piece on Mattis in June in which Mattis took a stick to Trump.

See James Mattis Denounces President Trump, Describes Him as a Threat to the Constitution

Twitter was flooded with condemnation of Trump after yesterday’s piece in The Atlantic; Team Trump sent out a horde of proxies like Sarah Huckabee Sanders to swat it down.

Not certain who’ll believe her.

Three Things: Breathing, Thinking, Mating and COVID-19

[NB: Check the byline, thanks. /~Rayne]

Breathing, thinking, mating.

At least one of these three things are important to you, no matter your age. COVID-19 can affect one or more of them, and we don’t yet know to what extent.

More importantly, it’s not getting through to the general public that COVID-19 can affect one or more of infected persons’ lungs, brain, and reproductive organs even if they are young, not to mention their heart and vascular system.

And by young I mean students in school, whether K-12 or tertiary (college/university) education.

~ ~ 3 ~ ~

But first, let’s talk about bad assumptions and biases.

We’ve heard since the earliest media reports from China that COVID-19 affected the lungs. It was characterized as a “pneumonia-like illness,” and unfortunately this characterization limited the public’s earliest perceptions of the disease.

“Pneumonia-like illness” allowed misinformation and disinformation to flourish — it’s just another flu, the propagandists propelled, ignoring the much greater mortality rate and the insufficient data about SARS-CoV-2’s transmissibility.

The health care system geared itself toward treating a “pneumonia-like illness,” demanding ventilators when ventilators might be fine for pneumonia, but might pose new risks with a disease like COVID-19. Health care workers performing endotracheal intubation, extubation, noninvasive ventilation were and are exposed to aerosolized virus material, requiring much greater rigor in personal protection due to these aerosol-generating procedures and the volume of virus they are exposed to each shift.

Even with increasing awareness that personal protection must be stepped up for COVID-19 as compared to influenza, hospitals still don’t have a handle on infection control. The Wall Street Journal reported:

“…Researchers at University of Nebraska Medical Center found the coronavirus in hallway air outside negative-pressure Covid-19 rooms. The Omaha hospital revamped its ventilation system to protect people in hallways by creating negative air flow there, too. …”

Existing negative air pressure rooms — Airborne Infection Isolation Rooms (AIIR) — might have been enough for influenza. It’s clearly not when 5,000 cases of COVID-19 may be related to inadequate infection controls in hospital settings in spite of like that used in dedicated COVID-19 treatment rooms. Hospitals would have changed their infection control protocols long ago had they seen nosocomial transmission of flu within hospitals approaching the rate of transmission with COVID-19, but perhaps the health care system has relied too heavily on annual flu vaccinations. Perhaps nosocomial transmission of flu and other pneumonia-like illness would have been much higher without vaccinations, revealing how flawed existing infection controls have been.

Our health care systems too slowly recognized COVID-19 isn’t like influenza or a pneumonia-like illness. It’s far more insidious. It’s now cost at least 600 health care workers their lives.

In addition to flawed assumptions, bias has also screwed up screening for COVID-19. Many of our community members know of people who were denied tests for COVID-19 because they didn’t meet certain criteria; one of the early criteria was whether the subject had traveled to China or been in contact with anyone who had been to China. Trump and his xenophobic followers have continued to exacerbate bias with racist framing of COVID-19.

Except that many cases of COVID-19 can be traced to Europe. It can be seen in the emergence and dominance of the G-lineage of the virus versus the D-lineage which was first common along the west coast. Everyone who had any one of the symptoms identified by China should have been tested for COVID-19, no matter where they had been or with whom they had been in contact.

I can’t begin to think about the number of lives which could have been saved had this country launched effective testing more widely, in concert with quarantine. But we didn’t in no small part because of limited, faulty thinking about COVID-19.

What other biases have similarly shaped our ability to address COVID-19 effectively?

The racist, ageist, ableist bias which informs inaction because it only negatively affects those people?

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We still don’t know what the repercussions are for recovered COVID-19 patients, including those who were asymptomatic.

Lung damage, which initially shaped health care professionals’ treatment as if COVID-19 was a pneumonia-like illness, appears to be long term.

Drillinger, M., Chesak, J. (fact checker) (2020, June 22). Lifelong Lung Damage: A Serious COVID-19 Complication. Retrieved July 27, 2020, from https://www.healthline.com/health-news/lifelong-lung-damage-the-serious-covid-19-complication-that-can-hit-people-in-their-20s

Damage was also seen in lungs of infected individuals who appeared to be asymptomatic or only mildly ill with COVID-19.

Prevalence of Asymptomatic SARS-CoV-2 Infection
Daniel P. Oran and Eric J. Topol
Annals of Internal Medicine, Reviews 3 Jun 2020
https://doi.org/10.7326/M20-3012

But it’s not just patients’ lungs affected; more than 36% of COVID-19 patients had neurological impairment.

Mao L, Jin H, Wang M, et al. Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China. JAMA Neurol. 2020;77(6):683–690. https://jamanetwork.com/journals/jamaneurology/fullarticle/2764549

Delirium, brain inflammation, stroke, and nerve damage occurred as well as a rare condition, acute disseminated encephalomyelitis (ADEM) — an inflammatory disorder which is sometimes fatal.

R W Paterson, R L Brown, L Benjamin et al, The emerging spectrum of COVID-19 neurology: clinical, radiological and laboratory findings, Brain, awaa240, Published: 08 July 2020
https://doi.org/10.1093/brain/awaa240
https://academic.oup.com/brain/article/doi/10.1093/brain/awaa240/5868408

The virus causes heart damage, even in patients who had no pre-existing cardiac disease:

In this global survey, cardiac abnormalities were observed in half of all COVID-19 patients undergoing echocardiography. Abnormalities were often unheralded or severe, and imaging changed management in one-third of patients.

Marc R Dweck, Anda Bularga, Rebecca T Hahn, Rong Bing, Kuan Ken Lee, Andrew R Chapman, Audrey White, Giovanni Di Salvo, Leyla Elif Sade, Keith Pearce, David E Newby, Bogdan A Popescu, Erwan Donal, Bernard Cosyns, Thor Edvardsen, Nicholas L Mills, Kristina Haugaa, Global evaluation of echocardiography in patients with COVID-19, European Heart Journal – Cardiovascular Imaging, , jeaa178, https://doi.org/10.1093/ehjci/jeaa178

Abnormalities found included myocardial infarction (heart attack), myocarditis (inflammation of heart tissue), takotsubo cardiomyopathy (temporary deformation of heart chamber), as well as elevated natriuretic peptides and cardiac troponin.

Scientific American published an article this weekend which offered even more anecdotal evidence of cardiac damage from COVID-19 even in asymptomatic persons.

Autopsies of COVID-19 victims showed damage to testicles:

Yang M, et al. Pathological Findings in the Testes of COVID-19 Patients: Clinical Implications. Eur
Urol Focus (2020), https://doi.org/10.1016/j.euf.2020.05.009
https://www.sciencedirect.com/science/article/pii/S2405456920301449

Based on findings, not only should kidney function and hormone levels be monitored but younger men should receive fertility counseling for family planning:

Wang, S., Zhou, X., Zhang, T. et al. The need for urogenital tract monitoring in COVID-19. Nat Rev Urol 17, 314–315 (2020). Published 20 April 2020 Issue Date June 2020
https://doi.org/10.1038/s41585-020-0319-7
https://www.nature.com/articles/s41585-020-0319-7

There have been many anecdotes of patients with sequelae lasting months after their initial illness. A large enough number exist for them to form groups in social media to compare notes about their experience. As the underlying SARS-CoV-2 virus is novel, we don’t have years of experience to look back upon for trends. We can’t yet predict whether there will be lifelong disability though many patients have reported development of diabetes, kidney dysfunction, heart disease, neurological impairment which have lasted months after they were technically deemed recovered. Studies on COVID-19’s long term effects have only recently begun and may last months to years.

We also don’t know how long any immunity post-infection will last, let alone whether most individuals can expect not to be re-infected within a year of their first infection. Brazil’s President Jair Bolsonaro is a recent obvious case raising questions about immunity; he tested positive for COVID-19 a third time two weeks after testing positive the first time.

So much for Bolsonaro’s faith in hydroxychloroquine as a therapy for COVID-19.

A British study showed immunity dropping within three months after recovery:

… In the first longitudinal study of its kind, scientists analysed the immune response of more than 90 patients and healthcare workers at Guy’s and St Thomas’ NHS foundation trust and found levels of antibodies that can destroy the virus peaked about three weeks after the onset of symptoms then swiftly declined.

Blood tests revealed that while 60% of people marshalled a “potent” antibody response at the height of their battle with the virus, only 17% retained the same potency three months later. Antibody levels fell as much as 23-fold over the period. In some cases, they became undetectable. …

Longitudinal evaluation and decline of antibody responses in SARS-CoV-2 infection
J Seow, C Graham, B Merrick, et al
medRxiv 2020.07.09.20148429; doi: https://doi.org/10.1101/2020.07.09.20148429
https://www.medrxiv.org/content/10.1101/2020.07.09.20148429v1

We’ve now seen cases where persons have recovered from COVID-19 only to be reinfected and sickened by a different strain. In a Hong Kong patient who had recovered in March but was reinfected during later travel to Spain, we see the problem of making assumptions based on bias about the “China flu.” COVID-19 isn’t just a single coronavirus strain originating in China.

The possibility of reinfection with different strains combined with decreasing immunity over time means reliance on “herd immunity” is foolhardy, and vaccines may not work as long as intended. Mitigating the spread of the disease remains crucial until a safe, effective, and durable vaccine has been developed, tested, and prepared for global distribution.

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If hearts and lungs, neurological and reproductive systems are permanently affected by COVID-19 even in younger patients who may remain asymptomatic, why risk exposing children and college-age students to COVID-19 by returning them back to in-classroom schooling?

You’d think white nationalists would clue in that their precious ideal of a white power future is threatened by this virus, literally neutered by testicular damage, but no — they insist students must return to school.

Worse, they insist on sports, demanding college football right now, even though athletes have been infected, sickened, suffered heart damage, and died from COVID-19 in spite of their youth and health.

Why are we even allowing in-classroom schooling at all when there has been zero effort to fund and implement modifications to HVAC systems though we have known for months now that aerosolized exhalation in poorly-ventilated enclosed spaces is the greatest risk factor to mass infection?

The only answer seems to be in the lack of any answer at all — the choice to do nothing is a choice.

And the choice the Trump administration, GOP legislators and state governors have made is to maim and kill more Americans.

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There’s an incredibly stupid tweet making the rounds, published by Students for Trump. They share a photo of Trump standing before burned-out buildings in Kenosha, Wisconsin. The tweet reads, “President @realDonaldTrump tours what Biden will do to America.

Most tweeters who comment remark on the idiocy of this projection: Trump stands before the wreckage he helped spur during the waning election year cycle as he runs for re-election.

I can’t help wonder if the stupidity of the tweet is a reflection of the damage exposure to COVID-19 may have already wrought on Students for Trump.

This is the future of the Republican Party: too brain damaged to recognize their reflection in the mirror.

Too impaired to recognize the self-inflicted injury, too messed up to save themselves and their future.

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This is an open thread, though COVID-19 content is preferred.

Place Your Bets: What’s Trump’s October Surprise? [UPDATE-2]

[NB: Check the byline, thanks! Updates will appear at the bottom of the post. / ~Rayne]

It’s become something of a American tradition — candidates pull something out of their asses in October which resets the calculus by which swing voters calibrate their darts before they aim at the board of presidential candidates.

Here are 180 years of surprises, though a few attempts aren’t squarely in October but rather late in the election season:

1840: Van Buren (D) vs. Harrison (W) — Van Buren’s fed prosecutors charged Whigs with voter fraud.

1880: Garfield (R) vs. Hancock (D) — The “Morey letter” purportedly written by Garfield implied Garfield favored Chines immigration.

1884: Cleveland (D) vs. Blaine (R) — Blaine said nothing in response to a popular bigoted preacher’s claim that Democrats promoted “rum, Romanism, and rebellion,” costing him Catholic and southern sympathizers’ votes.

1912: Taft (R) vs. Wilson (D) — Taft’s VP died a week before election day.

1920: Harding (R) vs. Cox (D) — Rumor of Harding’s “negro blood”, Roosevelt’s gays in Navy investigation.

1940: Roosevelt (D) vs. Willkie (R) — Roosevelt promoted African-American Colonel Benjamin O. Davis Sr. to brigadier general.

1964: Johnson (D) vs. Goldwater (R) — Jenkins’ gay sex scandal, Khruschev’s ouster, PRC’s first nuke test, September “Daisy” TV ad.

1968: Nixon (R) vs. Johnson (withdrew)/Humphrey (D) — Nixon undermined Johnson’s peace talks with Vietnam.

1972: Nixon (R) vs. McGovern (D) — Henry Kissinger’s “peace is at hand” remarks referring to the Vietnam war.

1980: Carter (D) vs. Reagan (R) — American hostages remained in Iran.

1992: Bush (R) vs. Clinton (D) — Caspar Weinberger’s indictment (really in June).

2000: Gore (D) vs. Bush (R) — George Bush’s drunk driving charge.

2004: Kerry (D) vs. Bush (R) — missing explosives cache, OBL tape, Saudi oil price cut, terror alerts.

2006: midterm elections — Mark Foley scandal, Saddam Hussein trial verdict.

2008: McCain (R) vs. Obama (D) — Revelation of Obama’s “illegal immigrant half-aunt” made the news.

2012: Romney (R) vs. Obama (D) — Romney’s “47%” tape was released.

2016: Clinton (D) vs. Trump (R) — “pussy grabber” tape + Wikileaks’ Podesta emails, Comey letter.

2018: midterm elections —  A “migrant caravan” materialized in Central America.

My gosh, October surprises going back as far as the Whig Party. Trump will be in good company if he aims beyond his sabotage of the U.S. Postal Service to obstruct Americans’ votes by throwing a late wrench in the works.

But what will that wrench be?

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There’s already been some speculation as to what kinds of ratfucking Trump will pull at the last moment. Two topics which some suggest may be used to generate October Surprises are the Durham investigation and a vaccine for COVID-19.

I don’t have a feel for the former. Marcy or bmaz might have a better sense of the likelihood. Can’t rule out there being more than one surprise, either. I put my money on the latter, though.

When it comes to the COVID-19 vaccine, we’re already seeing jockeying around this issue, including the news about Putin’s daughter having been a test subject for a COVID-19 vaccine candidate.

Unfortunately, Dr. Anthony Fauci has naively set up expectations for a vaccine by the end of the year.

… “From everything we’ve seen now — in the animal data, as well as the human data — we feel cautiously optimistic that we will have a vaccine by the end of this year and as we go into 2021,” said Fauci, director of the National Institute of Allergy and Infectious Diseases. “I don’t think it’s dreaming.” …

The problem is that he’s offered inadequate qualifications when asked for comment, though to be fair, this excerpt is from that awful hearing with Rep. Jim “Killer Clown” Jordan being an asshole to him.

It’s extremely doubtful there will be a safe and effective vaccine ready for nationwide or global deployment by the end of the year. There may be one or more candidates which are ready for varying stages of testing, trials, or regulatory approvals.

While there are numerous vaccines in development around the world, American pharma company Pfizer has a candidate nearing a benchmark:

… Pfizer has said repeatedly since June that it was targeting October for its application and the companies started a large late-stage study last month of the candidate vaccine, one of the few globally in later stages of development.

On Thursday they reported data from previous early-stage trials of the vaccine, BNT162b2, that showed it induced similar immune responses and had milder side effects than prior data on another candidate. …

October. Huh. What a coincidence. How odd its timing also syncs up with anticipated roll-out of Russia’s vaccine.

Do pay careful attention to that “milder side effects” bit. There’s a lot in these three words without enough explanation.

Trump’s veep-minion is singing a hopeful refrain, invoking some religious happy talk with the word “miracle”:

But this morning Trump had another temper tantrum via Twitter about the vaccine approval process:

No, you great tangerine dipshit. Speed should NOT be the focus unless you’re worried about re-election and need a Hail Mary pass delivered in October.

For the American public, the vaccine must be safe and effective. There are no shortcuts to these two deliverables, especially since this vaccine will be rolled out to the entire population, from children to elderly. We don’t want a vaccine which causes more problems than the disease it’s supposed to prevent.

Which is why the Food and Drug Administration needs to do its job thoroughly and with as much openness as the process and partners permit. But not with such speed that safety and efficacy are threatened.

What I can’t say is whether Trump’s temper tantrum is meant to pressure the FDA, or if it’s meant to condition the public to believe he is responsible for making the shortened vaccine development timeline happen, so when the FDA does get around to completing regulatory review, Trump can crow he alone can fix COVID-19.

Which is bullshit after 175,695 Americans have died of COVID-19 as of 11:00 p.m. ET today.

~ ~ ~

So what’s your take? What will be the October surprise Trump will attempt to save his ass this November?

This is an open thread.

 . . .

UPDATE-1 — 11:50 P.M. ET —

Son of a gun, just when I was going to log off and go to bed this crap pops up in my feed.

Great. We’re going to hear narcissistic dementia babble with some faux authoritative affirmation from a goddamned ONCOLOGIST and not an epidemiologist/virologist/public health MD about whatever dog-and-pony White House Coronavirus Taskforce stuff this is.

Where will the far-more-trusted Dr. Fauci be during this crap?

We all know the real point of this last minute lob into Saturday night’s dark is a means to change the subject of tomorrow morning’s Sunday talk shows.

The White House doesn’t want the punditocracy to talk about

1) The Democrats’ convention this past week and Joe Biden’s acceptance in particular;
2) Postmaster General Louis DeJoy’s appearance before the Senate and Steve Mnuchin’s role in the USPS crisis;
3) The Delivering for America Act, H.R. 8015 which passed the House today and now heads to the Senate;
4) The lack of action in the Senate on reconciling the House’s HEROES Act with the Senate’s awful HEALS Act;
5) The beginning of a massive eviction/foreclosure/homelessness crisis;
6) The failures of schools both K-12 and universities to safely relaunch;
7) Mary Trump’s audiotape of Trump’s sister Maryanne Trump Barry in which much tea is spilled about Trump;

and lastly, the ongoing mass death event costing 1200 American lives each day because Donald Trump is such an abjectly corrupt fuckup.

Add that to your predictions — of which item is Trump most afraid of that Team Trump had to manufacture a breakthrough to derail Sunday morning talk shows?

 . . .

UPDATE-2 — 7:15 P.M. ET —

Trump’s 6:00 p.m. presser has come and gone — a quickly slapped together sandwich of a racist anti-China dig, nonsensical back-patting and a ridiculous announcement, with a side of exactly three questions allotted to Fox News (2) and OAN (1) before fleeing the scene like a criminal.

What’s the likelihood the questions were pre-approved?

I am so fucking glad I didn’t turn on my television to watch this laughable circle jerk.

Politico published a story earlier this afternoon about the subject of this announcement: the use of plasma from COVID-19 survivors as pharmaceutical therapy for patients in severe condition, hospitalized with COVID-19.

Convalescent plasma is NOT a preventative therapy.

Experts like former CDC director Dr. Tom Friedan aren’t rah-rah about this therapy or announcement:

The one thing no one was able to ask Trump was whether he’s received this therapy. It’s possible he received a prophylactic dose; I can think of one occasion when it may have happened, three days after Herman Cain died.

Maybe this is the surprise which hasn’t yet been sprung on us yet?

Three Things: Numbers, Hearings and Racist Code

There’s always more than three things to address but here’s three we should look at more closely.

~ 3 ~
This is what we’re up against.

823 Americans have died of COVID-19 since yesterday. In contrast, South Korea, which learned of its first case of COVID-19 the same day the U.S. learned of its own, has only lost 281 of its citizens.

We lost not one American to an attempted shoe bombing in 2001 and yet an immediate program was developed and implemented to detect future shoe bombing attempts, requiring air travelers to take off their damned shoes and go through multiple screenings.

But Trump can’t be arsed to shut up and let the professionals handle stopping an ongoing daily stream of deaths from COVID-19.

This administration is killing Americans. Trump’s not even hiding the fact he’s willing to ignore deaths to manipulate numbers by insisting testing for the virus should be suppressed. He has the temerity to brag about his performance which has resulted in the unnecessary deaths of more than 120,000 Americans.

Yesterday the House Committee on Energy and Commerce held a hearing on oversight of the Trump Administration’s response to the COVID-19 pandemic.

Called to testify before the committee:

Robert R. Redfield, M.D., Director, Centers for Disease Control and Prevention (statement at 27:39)

Anthony S. Fauci, M.D., Director, National Institute for Allergy and Infectious Diseases, National Institutes o Health (at 33:40)

Admiral Brett P. Giroir, M.D., Assistant Secretary for Health, U.S. Department of Health and Human Services (at 38:25)

Stephen M. Hahn, M.D., Commissioner, U.S. Food and Drug Administration (at 43:54)

 

Some of the GOP’s efforts are useless, wasteful filibustering — like Rep. Bob Latta’s (OH-5) question about how the human body makes antibodies. This is something he should have been briefed on let alone read on his own long before this hearing. He should have read this basic biology question MONTHS AGO when the pandemic began. So was his question about how the vaccine would be distributed WHEN WE’RE 6-18 MONTHS OUT AT BEST from having a viable, effective, safe vaccine through Phase III trials.

Rep. Diana DeGette asked Fauci about vaccine development (at about 1:28:00); I think he was extremely optimistic saying he thought there would be one by early 2021. But the question wasn’t as specific as it should have been; there are clinical trials in progress for a couple of candidates, but it’s not clear what phase they are in.

Reported last week by StatNews:

There are more than 100 projects around the world centered on the development of a vaccine for the coronavirus. As of May 11, eight candidate vaccines were being tested in clinical trials in people.

An official at the National Institutes of Health said in mid-May that large-scale testing could begin in July with a vaccine potentially available by January.

Other experts say the more likely timeline is summer or fall of 2021.

The other factor beyond the capabilities of the vaccines and developers which will predict the time to public distribution is Congress and the White House.

If we still have that malicious narcissist in the Oval Office without a veto-proof Democratic majority in the Senate, nationwide roll-out of a vaccine by the U.S. government may not happen even if an efficacious vaccine is found.

Meanwhile, COVID-19 don’t care…

Just like Trump.

~ 2 ~
The Mary Sue presented a nice overview of what happened in Tulsa this past weekend.

In short, Team Trump fucked themselves hard.

What happened this weekend was supposed to be a point where Trump turned the narrative back in his favor and moved the attention away from the activists and change that have controlled the news cycle for months. But what really happened was instead of taking the attention away from the K-Pop teens for his failures, those things all combined to add one more line to an endless line of failures that we can only hope will keep going until November.

It wasn’t just a loss of narrative and momentum but the complete trashing of campaign data harvesting.

We don’t know exactly what the data accumulated by Trump’s re-election campaign looks like after receiving ~800,000 registrations for the Tulsa rally. Some were valid, some were valid but no-shows, some were legitimate addresses of people who had zero intention of attending — likely sent by TikTok accounts.

And a mess of them must have been K-pop fans who are still feeling their oats after they DDoS’d police video monitoring during anti-racism protests as well as spamming right-wing hashtags.

Parscale’s operation better have had a good backup before the Tulsa registrations began, though I have suspicions somebody’s ass wasn’t well covered.

I mean, who is foolish enough to brag about more than 1,000,000 registrations like that, without a hint of skepticism about the data’s integrity?

Somebody prone to hubris, that’s who.

And somebody else isn’t going to pay Team Trump for data gleaned through Tulsa.

~ 1 ~
The ACLU filed suit this morning against the Detroit Police Department for its wrongful arrest of Robert Williams based on racist facial recognition technology.

The Washington Post published an op-ed by Williams explaining what happened to him and why facial recognition software should be banned.

The next morning, two officers asked if I’d ever been to a Shinola watch store in Detroit. I said once, many years ago. They showed me a blurry surveillance camera photo of a black man and asked if it was me. I chuckled a bit. “No, that is not me.” He showed me another photo and said, “So I guess this isn’t you either?” I picked up the piece of paper, put it next to my face and said, “I hope you guys don’t think that all black men look alike.”

The cops looked at each other. I heard one say that “the computer must have gotten it wrong.” I asked if I was free to go now, and they said no. I was released from detention later that evening, after nearly 30 hours in holding. …

It’s not just the software at fault, though. DPD made absolutely no attempt to confirm Williams’ identity against images they had before they took him into custody, processed him, and detained him overnight in holding.

They literally can’t be bothered or they are racist as hell in a minority majority city.

The ACLU is calling for a ban on facial recognition in Detroit, Williams being a perfect example of how flawed and racist the technology is as well as an assault on innocent citizens’ privacy.

 

Boston’s city council banned facial recognition technology this morning, setting an example for Detroit.

What’s your municipality doing about facial recognition technology?

Are you blowing off this issue because you’re white and you couldn’t possibly be misidentified?

Sure.

~ 0 ~
The House Judiciary Committee hearing on politicization at the Justice Department is still under way as hit Publish. If you haven’t been following along and want to catch up, here are four Twitter threads covering the hearing.

Marcy https://twitter.com/emptywheel/status/1275821690170335237

Jennifer Taub https://twitter.com/jentaub/status/1275825424405323776

Courthouse News https://twitter.com/ByTimRyan/status/1275821746923417603

CNN https://twitter.com/jeremyherb/status/1275820657289428994

This is an open thread.

Three Things: Even More Family Fun with COVID-19

[Check the byline, thanks!/~Rayne]

I figured it would be the oldsters in the family who would be my first worry. The grandparents still go to church, play bridge and golf, volunteer; they’re living typical retirees’ lives. They haven’t stopped mingling socially until this week.

But no. Last week I had to worry about my younger kid at college first. Fortunately they only had strep.

Last night the older adult child called, complaining of a migraine, dry cough, wheezing, and a tight chest. They’d already called the doctor about their symptoms; the doctor wouldn’t order a test because older adult child didn’t have a temperature.

All the other symptoms of COVID-19 except for a temperature. With so few tests available in Michigan, unless my kid checked ALL the boxes, there’s no way they’d be tested.

We’re pretty sure it’s not flu because the symptoms were slow onset rather than fast and adult child had a flu shot this year.

The kicker is that someone at work tested positive for COVID-19. It just hadn’t been announced across the business, likely because the business still needed to finish its plan for handling this situation.

Because my adult child couldn’t get a test, their spouse can’t say they’ve been exposed to COVID-19 and is likely now at work, probably spreading this around if indeed my adult child has COVID-19.

I won’t see my older kid or their spouse for a least a month now since we don’t yet know for certain if they have COVID-19 let alone how long exposed persons may be contagious. I dare not take the chance to see them because of my autoimmune disorder — not just because I might come down with COVID-19, but because hospitals may not be able to offer me an adequate level of care if there are no hospital beds or ventilators if one was needed.

When I saw this bullshit tweet this morning I almost levitated.

All the stress of our not knowing individual infection status and potentially exposing even more Michiganders is due to Trump, who instead directs his animosity toward an effective governor who isn’t getting the support she needs from the federal government.

My family and many others in Michigan and across the country are going through this Kafkaesque circus of uncertainty because the grossly-incompetent-when-not-corrupt Trump administration chose not to do the right thing and roll out testing back in January-February so that community acquired infections could be pinpointed earlier.

The one piece missing in this equation: why is it some people can get tested and others can’t? What arbitrary ju-ju allows Oklahoma to offer up a sizable percentage of its available tests for the Utah Jazz basketball players? Why are some political figures able to summon a test when others can’t?

Is this an additional layer of fuckery, not only the limitations on the number of tests available but an invisible prioritization of who can be tested? Does one’s political party affiliation make a difference, or the color of their state when it comes to getting a test for COVID-19 on a timely basis?

~ 3 ~

The UK did an about-face in its approach toward COVID-19. Boris Johnson backed off the idiocy of allowing the virus to simply run amok through the population to kill its most vulnerable citizens as well as those with the misfortune of being severly to critically ill while UK hospitals are overwhelmed by COVID-19 case load.

However, in spite of the noise made over the Imperial College’s latest assessment of COVID-19’s impact on the UK, nothing is being done. Leadership may have made some noises of surprise over the published mortality numbers but there have been no orders to lock down the country the way France has this past week, or Italy before that.

Instead, Johnson urged Britons to avoid pubs, restaurants and theaters.

He asked that the public only use the NHS “where we really need to.”

Britons were asked to avoid non-essential travel.

In short, a guidance was issued which appears wholly optional. It has no teeth.

Most importantly, Johnson did not order the country’s schools shut down, though young people are believed to be vectors for the virus. Murdoch’s tabloid-y outlet The Sun reports Johnson “hints” at shutting down schools in a few days, though a petition gathered more than 650,000 signatures asking for Johnson to do so immediately.

These numbers were pointedly ignored, though there was moaning at the number of deaths projected by Imperial College’s report — an estimated 250,000 souls. Johnson’s actions to date do little to mitigate let alone suppress COVID-19’S contagion, choices Imperial College explained as approaches to minimizing deaths.

The number of deaths even if Johnson implemented a more aggressive suppression regime in Great Britain* is staggering…

(*Great Britain versus United Kingdom may explain why the numbers shown are lower than a thumbnail analysis based on 67M UK residents x 40% infection rate x 2% case fatality rate.)

\Johnson’s action to date fails to respond adequately to the swamping of UK’s health care system, particularly its intensive care systems.

This past weekend the country continued to go to pubs and concerts, looking much like the revelers partying at the Masque while the Red Death roamed outside the walls of the palace.

Being on an island will not protect them, nor will having expressed a desire to leave the EU.

We won’t be able to help them, either; Trump has done little more than Johnson has for the U.S., relying instead on the states to do the heavy lifting of saving American lives.

If we survive this next year, those of us who are most at risk will owe our lives to the efforts of governors like Gretchen Whitmer, who must not only make the impossible happen with limited resources, but with an ignorant, mean asshat president whining about them at the same time.

~ 2 ~

One of our community members Surfer2099 has been digging away at pharma company Gilead Sciences; the company makes an antiviral drug, remdesivir, which has been used off-label to treat COVID-19 patients. As noted before in previous posts, the medication was shipped to China for tests without normal approval of the FDA.

Bloomberg reported yesterday that China wants to patent remdesivir (link to story at Reddit). It looks like China wants the patent in exchange for having allowed Gilead to test its drug on COVID-19 patients, bypassing the FDA’s test protocols in the U.S.

Surfer2099 noted that Gilead coincidentally launched a merger and acquisition the first week of March. How does such a move fit into the negotiations with China?

Don’t look away from this as remdesivir appears to have widening support in the treatment of COVID-19. If it’s the only drug approved by drug agencies including the FDA, there’s considerable money to be made with tens of millions of COVID-19 patients anticipated over the next 1-2 years.

~ 1 ~

Fortunately there was a little good news yesterday. A COVID-19 vaccine was injected into the first human volunteer in a Phase 1 trial. If successful, the vaccine will not be available for the public for at least a year and likely longer.

NIH Clinical Trial of Investigational Vaccine for COVID-19 Begins

The realistic time frame from this first injection to a public vaccine is at least 12 to 20 months under the best conditions, i.e., no reactions, no other hiccups like supply problems, no interference from outside entities like the Trump administration.

That’s how long we need to practice social distancing — at least 12 to 20 months. Settle in and develop a routine for the long haul.

~ 0 ~

This is an open thread. How are your friends and family doing with the changes we’ve had to make to our lifestyles?